Systems BiologybioRxivPreprint
Competition between binding sites determines gene expression at low transcription factor concentrations
David van Dijk, Eilon Sharon, Maya Lotan-Pompan…·Lucas B. Carey
The paper measures promoter activity in budding yeast under varying TF concentrations and shows that competition between binding sites, not site number, determines gene expression, with a thermodynamic model explaining the results.
DOI 10.1101/033753