Non-enzymatic ABHD6 interacts with Akt-FoxO1 axis to regulate selective hepatic insulin resistance
Guannan Li, Laurence T. Maeyens, Jiyuan Yin, Jan‐Bernd Funcke, Chanmin Joung, Ruizhen Li, Ziying Xu, Z. Xu, Xin Li, Nisi Jiang, Mbolle Ekane, Maria Paula Lopez, Pengju Cao, Sijia He, Adam B. Salmon, , Shangang Zhao
This study identifies a non-enzymatic role of ABHD6 in regulating selective hepatic insulin resistance and MASLD through interaction with the Akt-FoxO1 axis.
bioRxiv · Feb 14, 2026 · PreprintPhysiology