GenomicsbioRxivPreprint
Caspase-Activated DNase Localizes to Cancer Causing Translocation Breakpoints During Cell Differentiation
Dalal Alsowaida, Brian Daniel Larsen, Sarah Hachmer…·Lynn A. Megeney
The paper identifies CAD-bound genes involved in both muscle cell differentiation and cancer-causing translocations, showing CAD-induced breaks are physiologic in differentiation and linked to oncogenic gene regulation.