NeurosciencebioRxivPreprint
Presymptomatic neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model of synucleinopathy
Stéphanie Tullo, Aline Silva de Miranda, Esther del Cid‐Pellitero…·M. Mallar Chakravarty
This study identifies neuroanatomical and cognitive biomarkers of alpha-synuclein propagation in a mouse model, showing early cognitive deficits and brain atrophy linked to prion-like spread of misfolded alpha-synuclein.