Melanie M. Chen

The paper identifies a Gabra2 variant that increases methamphetamine sensitivity using QTL analysis in mice and validates it with CRISPR correction.

This study investigates sex differences in behavioral and brainstem transcriptomic changes in mice exposed to neonatal opioids, finding sex-specific neuroadaptations linked to NOWS-like behaviors.

The paper identifies a dynamic hnRNP H RNA targetome in the striatum that responds to methamphetamine, affecting gene expression and behavior.

This study investigates the role of Hnrnph1 in fentanyl-induced behaviors, finding reduced sensitivity and reward in mutants with sex-specific effects.

This study shows that cuprizone reduces binge eating specifically in male C57BL/6NJ mice, suggesting sex-specific mechanisms influenced by genetic background.

This study shows that Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake in a parent-of-origin and genetic background-dependent manner in mice.

The paper identifies a major QTL on chromosome 7 associated with acute thermal nociception in C57BL/6 mouse substrains.