Systems BiologybioRxivPreprint
Evaluating the impact of NPC1 SNPs on entry efficiency of Filovirus in vitro: agent-based model approach
Ju Seong Kim, Kwang Su Kim, Ayato Takada…·Mi Jin Lee
The paper uses an agent-based model to quantify how specific NPC1 SNPs affect filovirus entry efficiency in vitro, finding that D508N, P424A, and S425L reduce entry efficiency for both Ebola and Marburg viruses.
DOI 10.1101/2025.03.13.642967