Cell BiologybioRxivPreprint
Hailey-Hailey disease models identify synergistic therapeutic effects of MEK and ROCK inhibition
Jessica Ayers, Arti Parihar, Afua Tiwaa…·Cory L. Simpson
This study uses human keratinocyte models of Hailey-Hailey disease to show that combined MEK and ROCK inhibition restores epidermal integrity, suggesting a therapeutic strategy for this genetic skin disorder.