Author

Michael Cashel

National Institutes of Health

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Molecular Biology· 1

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Organism:E. coli· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

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Elena V. SinevaiD· 1 shared Katsuhiko S. MurakamiiD· 1 shared Lu ZhangiD· 1 shared Sarah E. AdesiD· 1 shared Vadim MolodtsoviD· 1 shared Xuhui HuangiD· 1 shared

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Molecular BiologyMolecular CellPeer-reviewedFeb 22, 2018

Allosteric effector ppGpp potentiates the inhibition of transcript initiation by DksA

Vadim Molodtsov, Elena V. Sineva, Lu Zhang…·Katsuhiko S. Murakami

This study reports the X-ray crystal structures of E. coli RNA polymerase complexes with DksA and ppGpp, revealing how ppGpp enhances DksA's inhibition of transcription initiation.

101 citationstop 1%

E. coliprotein structure

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