Animal Behavior & CognitionBrain Behavior and ImmunityPeer-reviewed
Disruption of hippocampal mitochondrial function underlies opioid-induced postoperative cognitive dysfunction in aged rats
Stephanie M. Muscat, Nicholas P. Deems, Bryan D. Alvarez…·Ruth M. Barrientos
This study identifies hippocampal mitochondrial dysfunction as a key mechanism underlying opioid-induced postoperative cognitive dysfunction in aged rats and shows that mitochondrial rejuvenation can reverse memory deficits.
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