Author

Michael J. McLachlan

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Neuroscience· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander Eckehart UrbaniD· 1 shared Alexis MitelpunktiD· 1 shared Bradley J. Swanson· 1 shared Bruce J. AronowiD· 1 shared Carolin PurmanniD· 1 shared ChangHui PakiD· 1 shared Douglas F. LevinsoniD· 1 shared Eric E. BardesiD· 1 shared

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2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexander Eckehart UrbanORCID

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1 paper

Recent·Most cited

NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedMay 25, 2021

Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons

ChangHui Pak, Tamás Dankó, Vincent R. Mirabella…·Thomas Christian Südhof

This study validates that heterozygous NRXN1 deletions impair neurotransmitter release in human neurons across multiple labs, suggesting a human-specific synaptic dysfunction relevant for schizophrenia drug discovery.

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humanmouse

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