GenomicsbioRxiv
The shrinking human protein coding complement: are there fewer than 20,000 genes?
Iakes Ezkurdia, David Juan, Jose Manuel Rodriguez…·Michael Tress
The paper maps peptides from proteomics studies to human genes, finding that only 3% of 2,001 genes with non-protein-like features show peptide detection, suggesting many may not code for proteins.
DOI 10.1093/hmg/ddu309