Molecular BiologyJCI InsightPeer-reviewed
The Tryptophan Metabolizing Enzyme Indoleamine 2,3-Dioxygenase 1 Regulates Polycystic Kidney Disease Progression
Dustin T. Nguyen, Emily K. Kleczko, Nidhi Dwivedi…·Katharina Hopp
This study shows that IDO1 inhibition reduces ADPKD severity by altering the cystic immune microenvironment.
27 citations