GeneticsbioRxivPreprint
Interactions between non-prion and prion domains of Rnq1 direct formation of amyloid vs liquid-like aggregates and create transmission barriers
Sangeun Park, Dania M. Maldonado, Michele L. Kadnar…·Irina L. Derkatch
This paper investigates how a mutation in the non-prion domain of Rnq1 affects prion transmission and aggregation properties, showing it creates barriers to prion propagation and promotes liquid-like droplet formation.
DOI 10.1101/2025.01.14.633072