Evolutionary BiologybioRxiv
Retrovirus-derived RTL9 plays an important role in innate antifungal immunity in the eutherian brain
Fumitoshi Ishino, Johbu Itoh, Masahito Irie…·Tomoko Kaneko-Ishino
The paper shows RTL9, a retrovirus-derived gene, is essential for microglial antifungal immunity by degrading fungal zymosan in the brain.
DOI 10.3390/ijms241914884