Author

Miguel Fernandez

University of Valparaíso

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Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1

Frequent Co-Authors

Antonio Peña-PichicoiiD· 1 shared Felipe EcheverríaiD· 1 shared Juan Pablo CastilloiD· 1 shared Osvaldo Diez AlvareziD· 1 shared Ramón LatorreiD· 1 shared Willy R. Carrasquel-UrsulaeziD· 1 shared

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2026-2026 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Antonio Peña-PichicoiORCID

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1 paper

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedFeb 17, 2026

Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel

Felipe Echeverría, Antonio Peña-Pichicoi, Miguel Fernandez…·Ramón Latorre

This study shows that the γ1 subunit of BK channels increases the equilibrium constant for channel opening by destabilizing the closed state and enhancing voltage-sensor-pore coupling.

2 citations

electrophysiologyexperimental assay

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