GenomicsbioRxivPreprint
Resolving sub-clonal heterogeneity within cell-line growths by single cell sequencing genomic DNA
Enrique I. Velazquez-Villarreal, Shamoni Maheshwari, Jon M. Sorenson…·David Wesley Craig
The paper uses single-cell sequencing of genomic DNA to resolve sub-clonal heterogeneity in the COLO829 cell line, identifying four major sub-clones and explaining conflicting bulk sequencing results.
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