Author
University of CambridgeORCID 0000-0002-4789-3374Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Piyali Ganguli, Celia De Los Angeles Colomina Basanta, Amelia Acha‐Sagredo…·Jo Spencer
The paper investigates how CDKN2A and other 9p21 gene losses influence oesophageal cancer progression, finding context-dependent effects on survival and immune infiltration.
Lina Sieverling, Chen Hong, Sandra D. Koser…·Rehan Akbani
The paper analyzes whole-genome sequencing data from cancer samples to identify genomic footprints of telomere maintenance mechanisms, finding specific telomere variant repeat patterns associated with ATRX/DAXX mutations.
Kadir Caner Akdemir, Victoria T. Le, Sahaana Chandran…·Ludmil B. Alexandrov
The paper examines how somatic structural variations affect TAD boundaries and gene regulation in human cancers using whole genome sequencing data.
Enrique I. Velazquez-Villarreal, Shamoni Maheshwari, Jon M. Sorenson…·David Wesley Craig
The paper uses single-cell sequencing of genomic DNA to resolve sub-clonal heterogeneity in the COLO829 cell line, identifying four major sub-clones and explaining conflicting bulk sequencing results.
Bernardo Rodríguez–Martín, Eva G. Álvarez, Adrian Baez‐Ortega…·the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Network
The paper analyzes somatic retrotransposition events in 2,954 cancer genomes, identifying L1 insertions as significant contributors to structural variations and oncogenesis.
Sam Abujudeh, Sebastian S. Zeki, MCV van Lanschot…·Richard Calvin Turkington
The paper introduces conliga, a method for inferring high-resolution SCNA profiles from a low-cost and simple assay, addressing the need for affordable SCNA analysis in clinical settings.