Inhibition of granulocyte ROS production by opioids prevents regeneration
Elodie Labit, Lise Rabiller, Christophe Guissard, Mireille Andre, Christine Rampon, Corinne Barreau, Béatrice Cousin, Audrey Carriere, Margaux Raffin, Gilles Mithieux, Mohamad Ala Eddine, Bernard Pipy, Anne Lorsignol, Sophie Vriz, Cecile Dromard, Louis Casteilla
This study shows opioids inhibit regeneration by blocking granulocyte ROS production in vertebrates, and this effect can be reversed with an opioid antagonist.
bioRxiv · Aug 30, 2017 · PreprintPhysiology