Evolutionary BiologybioRxivPreprint
Purifying selection and adaptive evolution proximate to the zoonosis of SARS-CoV-1 and SARS-CoV-2
Jeffrey P. Townsend, Stephen Gaughran, Hayley B. Hassler…·Alex Dornburg
This study analyzes selection pressures in SARS-CoV-1 and SARS-CoV-2 genomes near zoonosis, finding strong purifying selection and limited positive selection, except for NSP12 and ORF7a.
DOI 10.1101/2023.08.07.552269