Author
Heinrich Heine University Düsseldorf
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
Önder Kurç, Nick Rähse, Mohanraj Gopalswamy…·Holger Gohlke
This study identifies two distinct carbohydrate-binding sites on CHI3L1, showing that chitin oligosaccharides and glycosaminoglycans bind to separate sites with different affinities and regulatory effects.
Annika Behrendt, Alex Bastianelli, Jan Stindt…·Holger Gohlke
This study identifies a missense variant in FXR that impairs its conformational transition to an active state, leading to reduced BSEP expression and a PFIC phenotype.
Xiaoli Yang, Pablo Cea‐Medina, Mohanraj Gopalswamy…·Stefanie Scheu
This study identifies Beauvericin as an uncompetitive inhibitor of Cathepsin B through NMR, enzyme kinetics, and molecular docking analyses in dendritic cells.
Mohanraj Gopalswamy, David Bickel, Niklas Dienstbier…·Holger Gohlke
The paper identifies non-charged analogs of the inhibitor 7.44 that show improved antiproliferative effects against RUNX1-ETO positive cells.