NeuroscienceScience AdvancesPeer-reviewed
An axon-intrinsic loop restricts nerve regeneration through axonal protein synthesis
Courtney N. Buchanan, Jinyoung Lee, Samaneh Matoo…·Jeffery L. Twiss
This study identifies an axon-intrinsic loop where REG3A promotes KHSRP translation, slowing nerve regeneration through localized mRNA synthesis and Ca2+ signaling.
DOI 10.1126/sciadv.aed0049