Author

Muhoon Lee

The University of Tokyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:Ribo-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Nono Takeuchi-TomitaiD· 2 shared Abdul Haseeb KhaniD· 1 shared Akira HigashibataiD· 1 shared Atsushi HigashitaniiD· 1 shared Brianna BibeliD· 1 shared Danica Galonić FujimoriiD· 1 shared Hironori SaitoiD· 1 shared James S. FraseriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Nono Takeuchi-TomitaORCID

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2 papers

Recent·Most cited

Context-specific inhibition of mitochondrial ribosomes by phenicol and oxazolidinone antibiotics

Brianna Bibel, Tushar Raskar, Mary Couvillion, Muhoon Lee, Jordan I. Kleinman, Nono Takeuchi-Tomita, L. Stirling Churchman, James S. Fraser, Danica Galonić Fujimori

This study investigates how chloramphenicol and oxazolidinone antibiotics inhibit mitochondrial ribosomes, finding context-specific stalling similar to their bacterial action.

Nucleic Acids Research · Jan 17, 2025Peer-reviewedBiochemistry

Gravitational and mechanical forces drive mitochondrial translation

Taisei Wakigawa, Yusuke Kimura, Mari Mito, Toshiya Tsubaki, Muhoon Lee, Koki Nakamura, Abdul Haseeb Khan, Hironori Saito, Tohru Yamamori, Tomokazu Yamazaki, Akira Higashibata, Tatsuhisa Tsuboi, Yusuke Hirabayashi, Nono Takeuchi-Tomita, Taku Saito, , Shintaro Iwasaki

The paper shows that gravity and mechanical forces influence mitochondrial translation by affecting signaling pathways and malonylation of the translational machinery.

bioRxiv · Jan 18, 2023 · PreprintMolecular Biology