Yusuke Hirabayashi

The paper reconstructs growth cones of callosal projection neurons in the developing mouse brain and finds they have a planar, dorsoventrally oriented morphology with filopodia that precede accelerated axon growth.

The paper develops a fluorescence lifetime-based sensor to image autophagy dynamics in vivo, revealing spatial and activity-dependent patterns in the mouse brain.

The paper develops a fluorescent sensor to image ER-mitochondria contacts in live cells and shows nutrient deprivation reduces these contacts via PDZD8.

This study identifies FKBP8 as the tethering partner of PDZD8 at ER-mitochondria contact sites, showing their interdependence in regulating mitochondrial morphology.

This study optimizes an AAV vector for efficient gene delivery to epidermal keratinocytes in vitro and in vivo by engineering capsid and promoter components.

The paper shows that most axonal mitochondria in mammalian neurons lack mtDNA and do not produce ATP, contrasting with dendritic mitochondria.

The paper shows that gravity and mechanical forces influence mitochondrial translation by affecting signaling pathways and malonylation of the translational machinery.

The paper investigates the role of intracellular Ca2+ release in shaping dendritic feature selectivity in hippocampal neurons during spatial navigation.

The paper introduces CoLSSEM, a method combining fluorescent labeling and electron microscopy to visualize synaptic connections in single neurons in vivo.