Enkephalin-mediated modulation of basal somatic sensitivity by regulatory T cells in mice
N. Aubert, M. Purcarea, J. Novarino, J. Schopp, A. Audibert, W. Li, M. Fornier, L. Cagnet, M. Naturel, A. Casrouge, N. Blanchard, M.-C. Dieu-Nosjean, G. Dietrich, C. Peirs, G. Marodon
This study shows that regulatory T cells modulate basal somatic sensitivity in mice through enkephalin production, with Penk expression regulated by TNF receptor family and Batf.
bioRxiv · Sep 12, 2023Immunology