Histone methyltransferase MMSET/NSD2 is essential for generation of B1 cell compartment in mice
M.-W. Dobenecker, V. Yurchenko, J. Marcello, A. Becker, E. Rudensky, N. Bahnu, T. Carrol, B. Garcia, B. Rosenberg, R. Prinjha, A. Tarakhovsky
This study identifies MMSET/NSD2 as essential for B1 cell development in mice, showing its role in histone methylation and B cell lineage specification.
bioRxiv · Jul 2, 2019 · PreprintImmunology