Author

A. Tarakhovsky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

R. Prinjha· 2 shared A. Becker· 1 shared A. Gerber· 1 shared B. A. Garcia· 1 shared B. D. Dill· 1 shared B. Garcia· 1 shared B. Rosenberg· 1 shared C. Adura· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

R. Prinjha

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transcriptional shut-off of MAP kinase signaling enables pluripotency maintenance during diapause

T. Zhang, R. J. Marina, R. Prinjha, K. Adelman, A. Tarakhovsky

The paper identifies that transcriptional repression via BET inhibition and upregulation of NRMKS genes maintains pluripotency in diapause ES cells by suppressing MAP kinase signaling.

bioRxiv · Dec 17, 2023 · PreprintCell Biology

Control of enhancer activation in the type I interferon response by the histone demethylase Kdm4d/JMJD2d

R. Chandwani, T. C. Fang, S. Dewell, A. Tarakhovsky

This study identifies Kdm4d/JMJD2d as a positive regulator of type I interferon responses by modulating enhancer RNA transcription and promoter demethylation.

bioRxiv · Jan 14, 2023Immunology

A histone-like motif in yellow fever virus contributes to viral replication

D. Mourao, S. Chen, U. Schaefer, L. Bozzacco, L. A. Carneiro, A. Gerber, C. Adura, B. D. Dill, H. Molina, T. Carroll, M. Paul, N. V. Bhanu, B. A. Garcia, G. Joberty, I. Rioja, , A. Tarakhovsky

This study identifies a histone-like motif in the yellow fever virus capsid protein that mimics histone H4 and interferes with BRD4-mediated gene regulation, impacting viral replication.

bioRxiv · May 5, 2020 · PreprintMicrobiology

Histone methyltransferase MMSET/NSD2 is essential for generation of B1 cell compartment in mice

M.-W. Dobenecker, V. Yurchenko, J. Marcello, A. Becker, E. Rudensky, N. Bahnu, T. Carrol, B. Garcia, B. Rosenberg, R. Prinjha, A. Tarakhovsky

This study identifies MMSET/NSD2 as essential for B1 cell development in mice, showing its role in histone methylation and B cell lineage specification.

bioRxiv · Jul 2, 2019 · PreprintImmunology