Dysregulation of PAX5 causes uncommitted B cell development and tumorigenesis in mice
B. Boast, K. Helian, D. Andrews, X. Li, V. Cho, A. Closa, H. J. Sutton, J. H. Reed, H. Bergmann, C. M. Roots, M. Yabas, N. Barthel, S. A. Omari, C. Young, L. A. Miosge, , A. Enders
Reduced PAX5 function in mice leads to uncommitted B cell development and B-ALL with secondary mutations in Jak3 and Ptpn11.
bioRxiv · Jan 29, 2021 · PreprintImmunology