Macrophage Function is Regulated by NPM1-Mediated 2'-O-Methylation
P. Sportoletti, D. Nachmani, L. Riccardi, A. Khanna-Gupta, J. Chen, A. Marra, N. Berliner, J. G. Clohessy, P. P. Pandolfi
This study shows that NPM1 regulates macrophage function through rRNA 2'-O-methylation and translation control, revealing a role in immune cell activity.
bioRxiv · Apr 18, 2020 · PreprintCell Biology