Cancer Stem Cell Enrichment and Metabolic Substrate Adaptability are Driven by Hydrogen Sulfide Suppression in Glioblastoma
D. J. Silver, G. A. Roversi, N. Bithi, C. K. A. Neumann, K. M. Troike, G. K. Ahuja, O. Reizes, J. M. Brown, C. Hine, J. D. Lathia
A high-fat diet accelerates glioblastoma by inhibiting hydrogen sulfide production, leading to cancer stem cell enrichment and reduced treatment response.
bioRxiv · Mar 8, 2020 · PreprintCancer Biology