Chemically modified dsRNA induces RNAi effects in insects in vitro and in vivo: A potential new tool for improving RNA-based plant protection
J. D. Howard, M. Beghyn, N. Dewulf, Y. De Vos, A. Philips, D. Portwood, P. M. Kilby, D. Oliver, W. Maddelein, S. Brown, M. J. Dickman
This study shows chemically modified long dsRNA improves RNAi efficacy in insects, leading to mortality in both cell cultures and live insects.
bioRxiv · Feb 2, 2022Bioengineering