Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid and IL4-Driven Macrophage Programming
D. K. Deochand, M. Dacic, M. J. Bale, A. W. Daman, S. Z. Josefowicz, D. Oliver, Y. Chinenov, I. Rogatsky
This study identifies shared and distinct mechanisms of macrophage programming by IL4 and glucocorticoids, revealing GRIP1's role in integrating their effects on transcription and function.
bioRxiv · Feb 16, 2024Immunology