Author

N. Engels

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:genetic perturbation / CRISPR· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1

Frequent Co-Authors

L. Wasim· 2 shared P. Tolar· 2 shared A. Rajavel· 1 shared B. Sale· 1 shared D. Malinova· 1 shared D. P. Calado· 1 shared F. Forconi· 1 shared F. Opazo· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

L. Wasim

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mutations in the IgG B cell receptor associated with class-switched B cell lymphomas

L. Wasim, S. W. T. Chu, B. Sale, L. Pickard, S. Leonard, L. Zhang, H. Tolarova, Z. S. Tean, N. Engels, D. P. Calado, K. Tarte, J. Okosun, F. Forconi, P. Tolar

This study identifies mutations in the IgG heavy chain in follicular lymphoma and EZB DLBCL that enhance BCR signalling and oncogenicity by disrupting the IgG intracellular tail.

bioRxiv · Apr 12, 2024 · PreprintImmunology

Endophilin A2 regulates B cell protein trafficking and humoral responses

D. Malinova, L. Wasim, N. Engels, P. Tolar

This study identifies endophilin A2 as essential for B cell endosomal trafficking, germinal center responses, and high-affinity IgG production through clathrin-independent mechanisms.

bioRxiv · Apr 20, 2020 · PreprintImmunology

A rationally designed and highly versatile epitope tag for nanobody-based purification, detection and manipulation of proteins

H. Goetzke, M. Kilisch, M. Martinez-Carranza, S. Sograte-Idrissi, A. Rajavel, T. Schlichthaerle, N. Engels, R. Jungmann, P. Stenmark, F. Opazo, S. Frey

The paper introduces the ALFA-tag, a versatile epitope tag that outperforms existing tags and enables multiple applications in protein detection, purification, and manipulation.

bioRxiv · Jun 7, 2019Biochemistry