Single cell transcriptomics reveals involution mimicry during the specification of the basal breast cancer subtype
F. Valdes-Mora, R. Salomon, B. S. Gloss, A. M. Law, L. Castillo, K. Murphy, J. Venhuizen, A. Magenau, M. Papanicolau, L. Rodriguez de la Fuente, D. L. Roden, Y. Colino-Sanguino, Z. Kikhtyak, N. Farbehi, J. R. Conway, , D. Gallego-Ortega
The paper uses single-cell RNA sequencing to show that basal breast cancer cells mimic involution processes, involving interactions with the tumor microenvironment to promote progression.
bioRxiv · May 16, 2020Cancer Biology