Induced pluripotent stem cell model revealed impaired neurovascular interaction in genetic small vessel disease CADASIL
W. Zhang, X. Zhao, X. Qi, S. J. Kimber, N. Hooper, T. Wang
This study uses iPSC-derived neurovascular cells to show impaired BBB function and disrupted tight junctions in CADASIL, highlighting early neurovascular interaction defects.
bioRxiv · Apr 26, 2023 · PreprintCell Biology