BiochemistrybioRxiv
Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets
DOI 10.1002/pro.4611
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2 papers
Recent·Most cited
M. Gao, I. G. P. Mackley, S. Mesbahi-Vasey…·J. F. Amacher
This study investigates the evolution of PDZ domain selectivity determinants in Monosiga brevicollis by analyzing crystal structures and binding affinities, finding conserved peptide selectivity with one exception.