TRAFfic signals: High-throughput CAR discovery in NK cells reveals novel TRAF-binding endodomains that drive enhanced persistence and cytotoxicity
M. D. Williams, A. T. Chen, M. R. Stone, L. Guo, B. J. Belmont, R. Turk, N. Bogard, N. Kearns, M. Young, B. Daines, M. Darnell
This study identifies TRAF-binding endodomains that enhance CAR NK cell persistence and cytotoxicity through high-throughput screening.
bioRxiv · Aug 2, 2023 · PreprintImmunology