Author

A. T. Chen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

B. Daines· 2 shared B. J. Belmont· 2 shared L. Guo· 2 shared M. D. Williams· 2 shared M. Darnell· 2 shared M. R. Stone· 2 shared M. Young· 2 shared N. Bogard· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

B. Daines

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Switching circuits: Modulating NK cell response to TGF-β using novel receptors

R. Turk, L. Guo, B. J. Belmont, N. Bogard, A. T. Chen, M. D. Williams, M. Young, M. R. Stone, B. Daines, M. Darnell

This study identifies novel switch receptors for NK cells that enhance cytotoxicity and persistence in the presence of TGF-β through a pooled screening approach.

bioRxiv · Dec 10, 2023 · PreprintImmunology

TRAFfic signals: High-throughput CAR discovery in NK cells reveals novel TRAF-binding endodomains that drive enhanced persistence and cytotoxicity

M. D. Williams, A. T. Chen, M. R. Stone, L. Guo, B. J. Belmont, R. Turk, N. Bogard, N. Kearns, M. Young, B. Daines, M. Darnell

This study identifies TRAF-binding endodomains that enhance CAR NK cell persistence and cytotoxicity through high-throughput screening.

bioRxiv · Aug 2, 2023 · PreprintImmunology

Peer teaching as bioinformatics training strategy: incentives, challenges, and benefits.

N.-T. Rahman, C. Meyer, D. Thakral, W. L. Cai, R. Garcia-Milian, A. T. Chen, R. Obaid

This study evaluates peer teaching workshops as a bioinformatics training strategy, identifying benefits like improved communication skills and challenges like time constraints and classroom management.

bioRxiv · Aug 26, 2021Scientific Communication & Education

Ex vivo dynamics of human glioblastoma cells in a microvasculature-on-a-chip system correlates with tumor heterogeneity and subtypes

Y. Xiao, D. Kim, B. Dura, K. Zhang, R. Yan, H. Li, E. Han, J. Ip, P. Zou, J. Liu, A. T. Chen, A. O. Vortmeyer, J. Zhou, R. Fan

This study uses a microvasculature-on-a-chip system to analyze ex vivo dynamics of human glioblastoma cells, showing correlations with tumor heterogeneity and subtypes.

bioRxiv · Sep 3, 2018Bioengineering