Author

M. Darnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. T. Chen· 2 shared B. Daines· 2 shared B. J. Belmont· 2 shared L. Guo· 2 shared M. D. Williams· 2 shared M. R. Stone· 2 shared M. Young· 2 shared N. Bogard· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. T. Chen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Switching circuits: Modulating NK cell response to TGF-β using novel receptors

R. Turk, L. Guo, B. J. Belmont, N. Bogard, A. T. Chen, M. D. Williams, M. Young, M. R. Stone, B. Daines, M. Darnell

This study identifies novel switch receptors for NK cells that enhance cytotoxicity and persistence in the presence of TGF-β through a pooled screening approach.

bioRxiv · Dec 10, 2023 · PreprintImmunology

TRAFfic signals: High-throughput CAR discovery in NK cells reveals novel TRAF-binding endodomains that drive enhanced persistence and cytotoxicity

M. D. Williams, A. T. Chen, M. R. Stone, L. Guo, B. J. Belmont, R. Turk, N. Bogard, N. Kearns, M. Young, B. Daines, M. Darnell

This study identifies TRAF-binding endodomains that enhance CAR NK cell persistence and cytotoxicity through high-throughput screening.

bioRxiv · Aug 2, 2023 · PreprintImmunology

Matrix viscoelasticity controls spatio-temporal tissue organization

A. Elosegui-Artola, A. Gupta, A. J. Najibi, B. R. Seo, R. Garry, C. M. Tringides, I. de Lazaro, M. Darnell, W. Gu, Q. Zhou, D. Weitz, L. Mahadevan, D. Mooney

This study shows how matrix viscoelasticity influences tissue organization by causing symmetry breaking and branching in epithelial cell aggregates.

bioRxiv · Jan 19, 2022 · PreprintBiophysics