BiophysicsbioRxiv
Interplay of folded domains and the disordered low-complexity domain in mediating hnRNPA1 phase separation
E. W. Martin, F. E. Thomasen, N. M. Milkovic…·T. Mittag
This study investigates how folded domains of hnRNPA1 modulate phase separation behavior of its disordered low-complexity domain, showing salt-dependent effects through electrostatic interactions and solubility changes.
DOI 10.1093/nar/gkab063