Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma
T. Nejo, L. Wang, K. K. Leung, A. Wang, S. Lakshmanachetty, M. Gallus, D. W. Kwok, C. Hong, L. H. Chen, D. A. Carrera, M. Y. Zhang, N. O. Stevers, G. C. Maldonado, A. Yamamichi, P. Watchmaker, , H. Okada
The paper identifies tumor-specific alternative splicing events in glioma that could generate cell-surface antigens but finds significant spatiotemporal heterogeneity and lack of proteomic evidence.
bioRxiv · Oct 26, 2023Cancer Biology