BiochemistrybioRxivPreprint
Regulation of shelterin proteins TERF2IP and TRF2 by H3K4me3-p65 axis drives hyperglycemia dependent endothelial senescence
S. Thakar, R. Bhattacharya, Y. T. Katakia…·S. Majumder
This study shows hyperglycemia increases TERF2IP and TRF2 via H3K4me3-p65 axis, driving endothelial senescence through p53 and p21 upregulation.
DOI 10.1101/2023.05.12.540614