Author

N. Pean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. ABDELRAFEE· 1 shared A. Le Lay· 1 shared A. Neves· 1 shared A. Rodriguez Martinez· 1 shared C. Magnan· 1 shared C. ULLMER· 1 shared D. Gauguier· 1 shared D. RAINTEAU· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPhysiology

A. ABDELRAFEE

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Bile Acid pool composition and Gallbladder function are controlled by TGR5 to protect the liver against Bile Acid overload

V. BIDAULT-JOURDAINNE, G. MERLEN, M. GLENISSON, I. DOIGNON, I. GARCIN, N. PEAN, R. BOISGARD, J. URSIC-BEDOYA, M. SERINO, C. ULLMER, L. HUMBERT, A. ABDELRAFEE, E. VIBERT, J.-C. DUCLOS-VALLEE, D. RAINTEAU, T. TORDJMANN

This study shows that TGR5 regulates bile acid pool composition and gallbladder function to protect the liver from bile acid overload in mice and humans.

bioRxiv · Feb 18, 2020 · PreprintPhysiology

The Microbial Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

F. Brial, F. Alzaid, K. Sonomura, K. Meneyrol, A. Le Lay, N. Pean, A. Neves, J. Chilloux, L. Hedjazi, T.-A. Sato, A. Rodriguez Martinez, N. Venteclef, J. K. Nicholson, C. Magnan, M. Lathrop, , D. Gauguier

This study identifies 4-cresol as a microbial metabolite that improves glucose homeostasis and β-cell function in preclinical models of cardiometabolic disease.

bioRxiv · Oct 16, 2018Physiology