Cancer BiologybioRxiv
Sex-biased ZRSR2 mutations in myeloid malignancies impair plasmacytoid dendritic cell activation and apoptosis
K. Togami, S. S. Chung, V. Madan…·A. A. Lane
The paper identifies sex-biased ZRSR2 mutations in BPDCN that impair pDC activation and apoptosis, linking X chromosome mutations to male-predominant leukemia.
DOI 10.1158/2159-8290.cd-20-1513