Author

N. Platt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

D. Shepherd· 2 shared F. M. Platt· 2 shared Y. Weng· 2 shared A. Galione· 1 shared B. Robertson· 1 shared G. C. Churchill· 1 shared G. Larrouy-Maumus· 1 shared N. Krishnan· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

D. Shepherd

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Release of acidic store calcium is required for effective priming of the NLRP3 inflammasome

N. Platt, D. Shepherd, Y. Weng, G. C. Churchill, A. Galione, F. M. Platt

This study shows that lysosomal Ca2+ release is essential for NLRP3 inflammasome priming and IL-1β production in mice with Niemann-Pick Type C or Tpcn1/Tpcn2 deficiency.

bioRxiv · Jan 6, 2022 · PreprintImmunology

Lipid mediated inhibition of Niemann-Pick C1 protein is an evolutionary conserved feature of multiple Mycobacterium lineages and non-tubercular mycobacteria.

F. M. Platt, Y. Weng, D. Shepherd, Y. Lu, N. Krishnan, B. Robertson, N. Platt, G. Larrouy-Maumus

This study investigates whether lipid extracts from various mycobacterial strains inhibit the NPC1 pathway, finding that inhibition occurs in most strains but not in Mycobacterium canettii.

bioRxiv · Sep 6, 2021 · PreprintMicrobiology