Author

N. Roumans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Carlier· 2 shared A. Schumacher· 2 shared A. Vasilevich· 2 shared F. Honig· 2 shared J. de Boer· 2 shared S. Vermeulen· 2 shared A. Dede Eren· 1 shared D. G. Hebels· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. Carlier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Enhanced microvasculature formation and patterning in iPSC-derived kidney organoids cultured in physiological hypoxia

A. Schumacher, N. Roumans, T. Rademakers, V. Joris, M. J. Eischen-Loges, M. van Griensven, V. LaPointe

This study shows that culturing kidney organoids in physiological hypoxia enhances endothelial network patterning and vascularization compared to normoxic conditions.

bioRxiv · Dec 22, 2021Cell Biology

Soft, dynamic hydrogel confinement improves kidney organoid lumen morphology and reduces epithelial-mesenchymal transition in culture

F. A. A. Ruiter, F. L. C. Morgan, N. Roumans, A. Schumacher, G. G. Slaats, L. Moroni, V. L. S. LaPointe, M. B. Baker

This study shows that soft, dynamic hydrogels improve kidney organoid morphology and reduce epithelial-mesenchymal transition compared to stiff hydrogels.

bioRxiv · Nov 10, 2021Bioengineering

Expanding Biomaterial Surface Topographical Design Space through Natural Surface Reproduction

J. de Boer, S. Vermeulen, F. Honig, A. Vasilevich, N. Roumans, A. Carlier, M. Romero, P. Williams, J. A. Uquillas

The paper expands the topographical design space of biomaterials by replicating natural surfaces and shows new cellular responses not observed with existing synthetic topographies.

bioRxiv · May 18, 2020Cell Biology

Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells

S. Vermeulen, N. Roumans, F. Honig, A. Carlier, D. G. Hebels, A. Dede Eren, P. ten Dijcke, A. Vasilevich, J. de Boer

The paper shows that surface topography enhances TGF-β signaling in mesenchymal stem cells through Rho/ROCK/SRF and PKC pathways, leading to increased expression of TGF-β target genes.

bioRxiv · Jan 13, 2020Cell Biology