MicrobiologybioRxiv
The ClpX chaperone controls the Staphylococcus aureus cell cycle but can be bypassed by β-lactam antibiotics
K. T. Baek, C. Jensen, C. Gallay…·D. Frees
This paper shows that β-lactam antibiotics can bypass the growth defect of S. aureus clpX mutants by restoring septum synthesis and preventing premature cell lysis.
DOI 10.1371/journal.ppat.1008044