An Inflammatory Clock Predicts Multi-morbidity, Immunosenescence and Cardiovascular Aging in Humans
N. Sayed, T. Gao, R. j. Tibshirani, T. Hastie, L. Cui, T. Kuznetsova, Y. Rosenberg-Hasson, R. Ostan, D. Monti, B. Lehallier, S. Shen-Orr, H. Maecker, C. L. Dekker, T. Wyss-Coray, C. Franceschi, , D. Furman
The paper develops an inflammatory clock of aging (iAge) using blood immunome data from 1001 individuals, showing it correlates with multi-morbidity, immunosenescence, and cardiovascular aging.
bioRxiv · Nov 16, 2019 · PreprintImmunology