Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes
Z. Lin, X. Wang, K. A. Bustin, L. He, R. M. Suciu, N. Schek, M. Ahmadi, K. Hu, E. J. Olson, W. H. Parsons, E. S. Witze, P. D. Morton, A. M. Gregus, M. W. Buczynski, M. L. Matthews
This paper introduces hydrazine-based chemoproteomic probes to target cofactor-dependent enzymes, enabling enzyme discovery and drug development through diverse functional profiling.
bioRxiv · Jun 17, 2020 · PreprintBiochemistry