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N. V. Kalmankar

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Plant Biology· 1

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Organism:C. elegans· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

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H. Hari· 1 shared R. Sowdhamini· 1 shared R. Venkatesan· 1 shared

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H. Hari

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Plant BiologybioRxivFeb 7, 2021

Disulfide-rich, cyclic peptides from Clitoria ternatea protect against β-amyloid toxicity and oxidative stress in transgenic Caenorhabditis elegans

N. V. Kalmankar, H. Hari, R. Sowdhamini, R. Venkatesan

This study shows that disulfide-rich cyclotides from Clitoria ternatea reduce β-amyloid toxicity and oxidative stress in C. elegans by inhibiting Aβ oligomerization and destabilizing amyloid assemblies.

DOI 10.1021/acs.jmedchem.1c00033

C. elegansproteomics

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