beta-blocker reverses inhibition of beta-2 adrenergic receptor resensitization by hypoxia
Y. Sun, M. K. Gupta, K. Stenson, M. L. Mohan, N. Wanner, K. Asosinght, S. Erzurum, S. N. Naga Prasad
This study shows hypoxia inhibits beta-2 adrenergic receptor resensitization by impairing PP2A activity via PI3Kgamma and I2PP2A phosphorylation, and beta-blockers reverse this effect.
bioRxiv · Sep 17, 2020 · PreprintBiochemistry